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  • ALS (Lou Gehrig’s Disease)
  • Alzheimer’s
  • Aplastic Anemia
  • Autism
  • Cardiomyopathy
  • Cartilage Repair
  • Cerebral Palsy
  • Crohn’s Disease
  • Connective Tissue Diseases
  • Diabetes
  • Liver Failure
  • Lung Injury
  • Lupus
  • Muscular Dystrophy
  • Multiple Sclerosis
  • Myocardial Infarction
  • Osteoarthritis
  • Parkinson’s
  • Rheumatoid Arthritis
  • Spinal Cord Injuries
  • Stroke
  • Traumatic Optic Neuropathy
  • Ulcerative Colitis
  • Wounds, Burns, Ulcers

The potential use of cord tissue stem cells for regenerative applications and to treat debilitating diseases is steadily increasing. Parents want to know they can count on the stem cells they have stored if they are ever needed. UMBI CELL PVT. LTD. umbilical cord tissue cryopreservation insures future clinical use in the event they are ever needed.

Cord blood stem cells have been used to treat nearly 80 diseases, including numerous types of malignancies, anemia’s, inherited metabolic disorders and deficiencies of the immune system.

The majority of cord blood transplants to date have been performed in patients younger than 18 years old. However, with the advancement in regenerative medicine, it is foreseeable that individuals of all ages can benefit from stem cell therapy in the near future. The source of cord blood used in transplants can be autologous (Self) or allogeneic (such as a sibling or an unrelated third party).

Graft - versus - host disease, a complication associated with stem cell transplant therapy, occurs less frequently with umbilical cord stem cells vs. other types of stem cells; and, it is even rarer when the cord stem cells come from a blood related family member. Below are some diseases currently being treated with stem cells. Although many cord blood stem cell treatments today are allogeneic (Non - Self), leading scientists believe that autologous (Self) cord blood will have a role in treating Type I diabetes, other autoimmune diseases, and brain and cardiac injuries.

Leukemias:

Leukemia is a cancer of the blood immune system, whose cells are called leukocytes or white cells (All Therapies are Allogeneic)
Acute Leukemia
  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Biphenotypic Leukemia
  • Acute Undifferentiated Leukemia
Chronic Leukemia
  • Chronic Myelogenous Leukemia (CML)
  • Chronic Lymphocytic Leukemia (CLL)
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
Myelodysplastic Syndromes (sometimes called Pre - Leukemia)
  • Refractory Anemia (RA)
  • Refractory Anemia with Ringed Sideroblasts (RARS)
  • Refractory Anemia with Excess Blasts (RAEB)
  • Refractory Anemia with Excess Blasts in Transformation (RAEB - T)
  • Chronic Myelomonocytic Leukemia (CMML)

Lymphomas:

Lymphoma is a cancer of the leukocytes that circulate in the blood and lymph vessels (All Therapies are Allogeneic)
  • Hodgkin’s Lymphoma
  • Non - Hodgkin’s Lymphoma (Burkitt’s Lymphoma)

Other Disorders of Blood Cell Proliferation

(All Therapies are Allogeneic)

Anemias

- Anemias are deficiencies or malformations of red cells (All Therapies are Allogeneic)
  • Aplastic Anemia
  • Congenital Dyserythropoietic Anemia
  • Fanconi Anemia (Note: the first cord blood transplant in 1988 was for FA, an inherited disorder)
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Pure Red Cell Aplasia

Inherited Red Cell Abnormalities

Red cells contain hemoglobin and carry oxygen to the body
  • Beta Thalassemia Major (also known as Cooley’s Anemia)
  • Blackfan - Diamond Anemia
  • Pure Red Cell Aplasia
  • Sickle Cell Disease


Inherited Platelet Abnormalities

Platelets are blood cells needed for clotting
  • Amegakaryocytosis / Congenital Thrombocytopenia
  • Glanzmann Thrombasthenia

Inherited Immune System Disorders - Neutropenias

  • Kostmann Syndrome
  • Myelokathexis

Inherited Immune System Disorders - Severe Combined Immunodeficiency (SCID)

  • SCID with Adenosine Deaminase Deficiency (ADA - SCID)
  • SCID which is X - linked
  • SCID with absence of T & B Cells
  • SCID with absence of T Cells, Normal B Cells
  • Omenn Syndrome

Inherited Immune System Disorders - Other

  • Ataxia - Telangiectasia
  • Bare Lymphocyte Syndrome
  • Common Variable Immunodeficiency
  • DiGeorge Syndrome
  • Leukocyte Adhesion Deficiency
  • Lymphoproliferative Disorders (LPD)
  • Lymphoproliferative Disorder, X - linked (also known as Epstein - Barr Virus Susceptibility)
  • Wiskott - Aldrich Syndrome

Myeloproliferative Disorders

  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Polycythemia Vera
  • Essential Thrombocythemia

Phagocyte Disorders

Phagocytes are immune system cells that can engulf and kill foreign organisms
  • Chediak - Higashi Syndrome
  • Chronic Granulomatous Disease
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis

Bone Marrow Cancers

(Plasma Cell Disorders)
  • Multiple Myeloma
  • Plasma Cell Leukemia
  • Waldenstrom’s Macroglobulinemia

Transplants for Inherited Disorders
Affecting the Immune System & Other Organs

(All Therapies are Allogeneic)
  • Cartilage - Hair Hypoplasia
  • Gunther’s Disease (Erythropoietic Porphyria)
  • Hermansky - Pudlak Syndrome
  • Pearson’s Syndrome
  • Shwachman - Diamond Syndrome
  • Systemic Mastocytosis

Transplants for Inherited Metabolic Disorders

(All Therapies are Allogeneic)

Mucopolysaccharidoses (MPS) Storage Diseases :

  • Mucopolysaccharidoses (MPS)
  • Hurler’s Syndrome (MPS - IH)
  • Scheie Syndrome (MPS - IS)
  • Hunter’s Syndrome (MPS - II)
  • Sanfilippo Syndrome (MPS - III)
  • Morquio Syndrome (MPS - IV)
  • Maroteaux - Lamy Syndrome (MPS - VI)
  • Sly Syndrome, Beta - Glucuronidase Deficiency (MPS - VII)
  • Mucolipidosis II (I - Cell Disease)

Leukodystrophy Disorders:

  • Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN)
  • Krabbe Disease (Globoid Cell Leukodystrophy)
  • Metachromatic Leukodystrophy
  • Pelizaeus - Merzbacher Disease

Lysosomal Storage Diseases:

  • Gaucher Disease
  • Niemann - Pick Disease
  • Sandhoff Disease
  • Tay - Sachs Disease
  • Wolman Disease

Inherited Metabolic Disorders - Other:

  • Lesch - Nyhan Syndrome
  • Osteopetrosis

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The Umbicell comprises Skilled and Experienced Researcher with the shared long-term aim of using their combined scientific and clinical expertise to promote stem cell therapies for patient benefit.

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